Pharma Acrylic Co-polymers comprise Ideal Cures innovative brand of specialty products providing delayed release/enteric film coatings to drug-substance tablets requiring protection from the acidic environment in the stomach. These coatings also provide protection to the gastric mucosa from any local concentrations of any drug substances that could cause gastric irritation.
The Acrylic Co-polymers grades are available to take care of the enteric coating requirements in the entire gastro-intestinal tract and may also provide a means of colonic delivery with site specific drugs.
The range of Acrylic Co-polymers provides the capability for use with aqueous, organic or hydro-alcoholic solvents thus providing the versatility needed for use with all types of film coating equipment and processes. Applications include tablets, capsules, powders, pellets for Pharmaceutical, Herbal and Nutraceutical formulations.
The most widely used acrylic co-polymers for enteric film coating are based on Methacrylic Acid, Ethyl Acrylate and Methyl Methacrylates. Ideal Cures offers
Use the recommended reconstitution solvent system and follow the guidelines stated.
|Parameters||Auto coater||Conventional Pan|
|Solids content (% w/w)||8.0||8.0||8.0||8.0||8.0|
|Pan speed* (rpm)||10-14||3-5||1.5-3||18-20||8-12|
|Tablet bed temperature (ºC)||30 – 35||30 – 35||30 – 35||30 – 35||30 – 35|
|Spray nozzle (mm)||1||1.2-1.5||1.2-1.5||1||1.2|
|Number of spray guns||1||2-3||4-6||1||1|
|Atomizing air pressure (bars)||1.5-2.5||2-2.8||2-3.0||1.2-1.8||1.5-2.2|
|Spray rate (g/min)||20-25||120-140||200-250||4-8||50-60|
|Inlet air temperature (ºC)||40-50||40-50||40-50||40-50||40-50|
|Weight gain (%)||8||8||8||8||8|
* Pan speed would depend upon the tablet shape, size, friability and the number of baffles, so as to effect proper mixing during the coating process.
** Tablet charge may vary depending upon the tablet shape and size.