Coatings for nutritional products


INSTANUTE Delayed Release

Product Description

INSTANUTE DR is a ready-to-use film coating system, based on Sodium Alginate which confers pH/solubility characteristics, making it suitable for nutritional applications requiring delayed release properties. It is supplied in a wide range of colours. Selection can be easily made from the INSTANUTE Colour Guide (available on request). INSTANUTE DR can be formulated with aluminium lake, iron oxides and natural pigments and can also include flavours.

Features Benefits


  • Dry powder system for reconstitution
  • Process time savings from rapid coating suspension manufacture
  • Complete coating formulation minus solvent
  • Cost savings in inventory and inventory management
  • Advanced colour control methods
  • Reproducible finished product appearance
  • Avoidance of customer complaints
  • White or ready coloured systems matched to your specification or sample are available. Anti-counterfeiting and branding features can be built-in
  • Meeting diverse marketing requirements is facilitated
  • Colours used are checked for compliance with appropriate regulations in target markets
  • Avoidance of regulatory issues


  • Sodium Alginate is a polymer of natural origin having pH sensitive dissolution characteristics, with a history of use in film coating
  • Easy to formulate, use and scale-up
  • Sodium Alginate is water soluble at neutral pH
  • Sodium Alginate is acid insoluble
  • Ideal properties for delayed release coating
  • Rapid reconstitution in water contributes to process speed and consequent time/cost savings
  • Aqueous processing promotes a safe working environment and avoidance of atmospheric pollution
  • Designed specifically to meet the regulatory requirements for dietary supplements, nutritional and herbal products in Europe, the United States and other North American regions.
  • Multiple country use is facilitated
  • Can be applied in a wide range of equipment designs and sizes from most manufacturers
  • Easy scale-up and transfer to different equipment types or manufacturing sites

Regulatory information

All products are checked for the regulatory compliance of all ingredients in the target countries and market segments of sale. This determination is made at the time the initial formulation is established, based on customer-supplied information. If market countries and/or segments are extended once the formulation has been established, customers are encouraged to contact us to ensure that regulatory compliance is not compromised.

Recommended Solvent System and Reconstitution Level

  • Purified water at up to 9% w/w solids

Equipment / Accessories

  • Variable-speed mechanical stirrer
  • Mixing Vessel

Calculation of INSTANUTE DR and solvent quantities

  • Determine the quantities of INSTANUTE DR (9% w/w solids) and water required based on the quantity of tablets to be coated and the target coating weight gain. e.g.: For coating 1.0 kg of tablets to 12% wt. gain, weigh 132 g Instacoat and 1335 gm purified water at room temperature (includes 10% overage for losses)

Reconstitution Process

  • Add the weighed quantity of water to a mixing vessel.
  • Using a mechanical stirrer, stir the purified water to form a vortex.
  • Add the required quantity of INSTANUTE DR to the centre of the liquid vortex in a slow steady stream, avoiding clumping while maintaining a vortex. Once the entire quantity of Instacoat has been added, reduce the stirrer speed to eliminate the vortex. Continue mixing for 45 minutes.

Recommended Process Conditions

(fully perforated) pans
(non perforated) pans
Pan diameter (inch) 24-60 12-36
Tablet load (kg) 10-300 0.5-50
Weight gain (%) 12.0
Number of guns 1-6 1
Liquid nozzle diameter (mm) 1.0-1.5
Atomising air pressure (bar) 2.0-3.5
Pattern air pressure To achieve maximum uniform bed coverage
Tablet bed temperature (⁰C) 42-45
Inlet air temperature (⁰C) Set to achieve required product bed temperature
Suspension spray rate Set to achieve required product bed temperature
Exhaust air volume To maintain slight negative pressure in pan
Pan speed Minimum for steady tablet flow through spray zone

*Tablet bed temperature offers the most effective way of controlling the coating process. Where this measurement is unavailable, exhaust temperature may be substituted. However, the relationship between the two measurements is complex and depends on several factors such as pan load, pan depression, pan design and airflow rate. Indicated exhaust temperature may be above or below the true bed temperature. It is recommended that the relationship between the two measurements is calibrated..

Typical Constituents

Sodium Alginate; Plasticiser; Titanium Dioxide; Edible Pigments; Microbiological Preservative.